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High performing athletes may often describe “hitting a wall” when pushing themselves during training or competition. This occurs at the depletion of their glycogen (carbohydrate) stores, which causes a sudden onset of fatigue and loss of athletic performance. Performing too close (or above) your anaerobic threshold will bring this effect on quicker, as at these high heart rates most athletes have moved beyond fat metabolism as a fuel and are relying on carbohydrate stores.
Weight loss is a complicated topic that's filled with many opinions, fad diets and at times, misinformation. There's often an assumption that "one-size-fits-all", and the methods that were effective for one person will work for everyone else. If only it was that easy...
You should be aiming to achieve an "energy in / energy out" balance. This means balancing the food we consume to give us energy, to power us appropriately for all the activities that we do during the day. Ideally, if we took an average across several weeks, the input from our diet will match the output from our activities without a significant deficit or excess present.